Home » Pharmacology » Potassium Channel Openers
Nicorandil acts in three ways:
- Releases NO leading to vasodilatation, decreasing preload and afterload
- Hyperpolarization, leading to relaxation of blood vessels
- Helps by virtue of preconditioning of myocardium. The myocardium contains K+ channels (ATP gated) also found n pancreas associated with insulin release. They reduce overloading of Ca++ reducing contractility, this is called reconditioning.
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Potassium Channel Openers – howMed
Home » Pharmacology » Potassium Channel Openers
Nicorandil acts in three ways:
Continue Reading
Drug Treatment of Ischemic Heart Disease
Organic Nitrates
Calcium Channel Blockers in Ischemic Heart Disease
Browse all articles on Cardiovascular System
2012-07-03
Editor
Check Also
Alkylating agents are the broad spectrum agennts. Chemistry Different reactive moiety: Bis (chloroethyl) amine / …