Editor – Page 60 – howMed

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Causes of Poisoning occupational poisoning homicidal accidental In the battle field, soldiers are at risk of poisoning, so they are …

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Pyridostigmine Muscarinic effects are less marked, more nicotinic effects Duration of action is long (6 hours) than neostigmine Use: Myasthenia …

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Natural alkaloid obtained from “Physostigma Venenosum”. It is a tertiary amine derivative, crosses blood brain barrier and is highly lipid …

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Structure Quaternary ammonium compound. Mode of action Neostigmine has dual action: Directly by binding neuromuscular ‘N’ receptors Indirectly by inhibiting …

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Anticholinesterases inhibit the enzymes acting upon acetylcholine. They are the inhibitors of Cholinesterases:- Acetyl cholinesterase (AchE) Butyryl cholinesterase (BChE) Classification …

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Alkaloids liquid in nature, obtained from plant source. Actions are mainly on nicotinic receptors (CNS, PNS, NMJ) Effects CNS, have …

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Muscarine Quaternary amine (Amanita muscaria) Poorly soluble, less complete absorption from the GIT Very toxic & can even enter the …

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Structure related to Acetylcholine, acetate is replaced by carbamate & choline is methylated, thus it is carbomyl beta methyl choline. …

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Methacholine has methyl group in its structure. It is more resistant to hydrolysis by choline esterase. It has both muscarinic …

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Carbachol is the ester of carbamic acid, having both muscarinic and nicotinic actions. Muscarinic actions are prominent on eye, GIT …

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