Tumors of small intestine may be classified, based on histology, into:
1. Epithelial tumors:
a. Adenoma i. Tubular ii. Villous
iii. Tubulovillous
b. Intraepithelial neoplasia (dysplasia) associated with chronic inflammatory diseases i. Low-grade glandular intraepithelial neoplasia
ii. High-grade glandular intraepithelial neoplasia
c. Carcinoma: i. Adenocarcinoma ii. Mucinous carcinoma iii. Signet-ring cell carcinoma iv. Small cell carcinoma v. Squamous cell carcinoma vi. Adenonsquamous carcinoma vii. Medullary carcinoma
viii. Undifferentiated carcinoma
Carcinoid tumor of small intestine
d. Carcinoid tumor (Well differentiated endocrine neoplasm) i. Gastrin cell tumour, functioning (gastrinoma) or nonfunctioning ii. Somatostatin cell tumour iii. EC (Enterochromafin) cell, serotonin-producing neoplasm
iv. L-cell, glucagon like peptide and PP (Pancreatic polypeptide)/PYY (Polypeptide YY)-producing tumour
e. Mixed carcinoid-adenocarcinoma
f. Gangliocytic paraganglioma
g. Others
2. Non-Epithelial tumors:
a. Lipoma b. Leiomyoma c. Gastrointestinal stromal tumour d. Leiomyosarcoma e. Angiosarcoma f. Kaposi sarcoma
g. Others
3. Malignant Lymphomas:
a. Immunoproliferative small intestinal disease (includes alpha-heavy chain disease) b. Western type B-cell lymphoma of MALT c. Mantle cell lymphoma d. Diffuse large B-cell lymphoma e. Burkitt’s lymphoma f. Burkitt like or atypical Burkitt’s lymphoma
g. T-cell lymphoma
- Enteropathy associated
- Unspecified
h. Others
4. Secondary Tumors
5. Polyps:
a. Hyperplastic (metaplastic) b. Peutz-Jeghers
c. Juvenile
Classification of Tumors of Small Intestine – howMed
Tumors of small intestine may be classified, based on histology, into:
1. Epithelial tumors:
a. Adenoma i. Tubular ii. Villous
iii. Tubulovillous
b. Intraepithelial neoplasia (dysplasia) associated with chronic inflammatory diseases i. Low-grade glandular intraepithelial neoplasia
ii. High-grade glandular intraepithelial neoplasia
c. Carcinoma: i. Adenocarcinoma ii. Mucinous carcinoma iii. Signet-ring cell carcinoma iv. Small cell carcinoma v. Squamous cell carcinoma vi. Adenonsquamous carcinoma vii. Medullary carcinoma
viii. Undifferentiated carcinoma
Carcinoid tumor of small intestine
d. Carcinoid tumor (Well differentiated endocrine neoplasm) i. Gastrin cell tumour, functioning (gastrinoma) or nonfunctioning ii. Somatostatin cell tumour iii. EC (Enterochromafin) cell, serotonin-producing neoplasm
iv. L-cell, glucagon like peptide and PP (Pancreatic polypeptide)/PYY (Polypeptide YY)-producing tumour
e. Mixed carcinoid-adenocarcinoma
f. Gangliocytic paraganglioma
g. Others
2. Non-Epithelial tumors:
a. Lipoma b. Leiomyoma c. Gastrointestinal stromal tumour d. Leiomyosarcoma e. Angiosarcoma f. Kaposi sarcoma
g. Others
3. Malignant Lymphomas:
a. Immunoproliferative small intestinal disease (includes alpha-heavy chain disease) b. Western type B-cell lymphoma of MALT c. Mantle cell lymphoma d. Diffuse large B-cell lymphoma e. Burkitt’s lymphoma f. Burkitt like or atypical Burkitt’s lymphoma
g. T-cell lymphoma
h. Others
4. Secondary Tumors
5. Polyps:
a. Hyperplastic (metaplastic) b. Peutz-Jeghers
c. Juvenile